Designing Clinical Research

Designing Clinical Research PDF Author: Stephen B. Hulley
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781782104
Category : Medical
Languages : en
Pages : 388

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Book Description
This third edition sets the standard for providing a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This edition incorporates current research methodology and offers an updated syllabus for conducting a clinical research workshop.

Designing Clinical Research

Designing Clinical Research PDF Author: Stephen B. Hulley
Publisher: Lippincott Williams & Wilkins
ISBN: 9781608318049
Category : Medical
Languages : en
Pages : 367

Get Book

Book Description
"This book provides a practical guide to planning, tabulating, formulating, and implementing clinical research, in an easy-to-use, readable presentation"--Provided by publisher.

Designing Clinical Research

Designing Clinical Research PDF Author: Warren S. Browner
Publisher: LWW
ISBN: 9781975174408
Category :
Languages : en
Pages : 472

Get Book

Book Description
"For over 30 years, this title sets the standard as a practical guide for physicians, nurses, pharmacists and other practitioners involved in all forms of clinical and public health research. It presents the epidemiologic concepts in a reader-friendly way and suggests common sense approaches to the challenging judgments involved in designing, funding and implementing a study. Translated in many languages over the years, it is a manual for clinical research in it various flavors: clinical trials, observational epidemiology, translated science, patient-oriented research. Epidemiologic- terms and principles, presented advanced conceptual material in a practical and reader friendly way and suggested common sense approaches to many judgments involved in designing a study"--

Planning and Designing Clinical Research

Planning and Designing Clinical Research PDF Author: S.B. Martins
Publisher: Springer
ISBN: 9788847001398
Category : Medical
Languages : en
Pages : 48

Get Book

Book Description
This manuscript is an introduction to the design and planning of clinical research. Practical issues are covered with a theoretical background. The refinement of a research question, searching and critically appraising the literature and management of references are discussed. Ethical concerns are raised throughout the development of the study protocol. Study designs are described and special emphasis is given to writing a protocol of a clinical trial. Sample selection and recruitment, variable measurement, randomization, follow up, statistical analysis, sample size and bias are covered. Tips on how to successfully write and publish the research report are provided.

Handbook for Clinical Research

Handbook for Clinical Research PDF Author: Flora Hammond, MD
Publisher: Demos Medical Publishing
ISBN: 1936287544
Category : Medical
Languages : en
Pages : 348

Get Book

Book Description
The majority of physicians are poorly knowledgeable about statistics and research design, yet are expected to do clinical research and write articles (if in academia) or, at the very least, to read the literature critically and provide evidence-based care to patients. The basic skills involved are touched on very minimally in residency, but not in enough depth for an untrained investigator to successfully design or conduct a study, or analyze research findings in any meaningful way. This volume is intended as a “quick fix”, allowing readers to look up information rapidly about various design types and statistical methods to see what the pros, cons, and indications for each are. Research implementation, including regulatory issues and grant writing, is also covered. The book is unique in physical medicine and rehabilitation, and with the increased emphasis on outcomes measurement and push toward a national agenda for disability research, will appeal both to investigators planning and executing studies and clinicians looking to better understand how the findings impact their practice. A list of topics with an outline of headings for each of the sections is attached.

Clinical Trial Design

Clinical Trial Design PDF Author: Guosheng Yin
Publisher: John Wiley & Sons
ISBN: 0470581719
Category : Medical
Languages : en
Pages : 368

Get Book

Book Description
A balanced treatment of the theories, methodologies, and design issues involved in clinical trials using statistical methods There has been enormous interest and development in Bayesian adaptive designs, especially for early phases of clinical trials. However, for phase III trials, frequentist methods still play a dominant role through controlling type I and type II errors in the hypothesis testing framework. From practical perspectives, Clinical Trial Design: Bayesian and Frequentist Adaptive Methods provides comprehensive coverage of both Bayesian and frequentist approaches to all phases of clinical trial design. Before underpinning various adaptive methods, the book establishes an overview of the fundamentals of clinical trials as well as a comparison of Bayesian and frequentist statistics. Recognizing that clinical trial design is one of the most important and useful skills in the pharmaceutical industry, this book provides detailed discussions on a variety of statistical designs, their properties, and operating characteristics for phase I, II, and III clinical trials as well as an introduction to phase IV trials. Many practical issues and challenges arising in clinical trials are addressed. Additional topics of coverage include: Risk and benefit analysis for toxicity and efficacy trade-offs Bayesian predictive probability trial monitoring Bayesian adaptive randomization Late onset toxicity and response Dose finding in drug combination trials Targeted therapy designs The author utilizes cutting-edge clinical trial designs and statistical methods that have been employed at the world's leading medical centers as well as in the pharmaceutical industry. The software used throughout the book is freely available on the book's related website, equipping readers with the necessary tools for designing clinical trials. Clinical Trial Design is an excellent book for courses on the topic at the graduate level. The book also serves as a valuable reference for statisticians and biostatisticians in the pharmaceutical industry as well as for researchers and practitioners who design, conduct, and monitor clinical trials in their everyday work.

Clinical Trials Design in Operative and Non Operative Invasive Procedures

Clinical Trials Design in Operative and Non Operative Invasive Procedures PDF Author: Kamal M.F. Itani
Publisher: Springer
ISBN: 3319538772
Category : Medical
Languages : en
Pages : 495

Get Book

Book Description
The aim of this text is to provide the framework for building a clinical trial as it pertains to operative and non operative invasive procedures, how to get it funded and how to conduct such a trial up to publication of results The text provides all details of building a scientifically and ethically valid proposal, including how to build the infrastructure for a clinical trial and how to move it forward through various funding agencies. The text also presents various types of clinical trials, the use of implantable devices and FDA requirements, and adjuncts to clinical trials and interaction with industry Clinical Trials Design in Invasive Operative and Non Operative Procedures will be of interest to all specialists of surgery, anesthesiologists, interventional radiologists, gastroenterologists, cardiologists, and pulmonologists

Clinical Research

Clinical Research PDF Author: Manfred Stommel
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781735186
Category : Medical
Languages : en
Pages : 484

Get Book

Book Description
This unique textbook integrates statistical concepts into evidence-based clinical practice and patient management. Research concepts and techniques are drawn from epidemiology, bio-statistics, and psychometrics, as well as educational and social science research. Clinical examples throughout the text illustrate practical and scientifically sound applications of the concepts. Data tables and research vignettes highlight statistical distributions involving probability. Methods to locate and utilize web-based information relevant to clinical research are discussed, and web URLs are provided. Further learning is encouraged by the inclusion of suggested activities, recommended readings, references, and a comprehensive glossary of research terms. Additional resources are available at a Connection Website, connection.LWW.com/go/stommel.

Publishing and Presenting Clinical Research

Publishing and Presenting Clinical Research PDF Author: Warren S. Browner
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781795067
Category : Medical
Languages : en
Pages : 230

Get Book

Book Description
This book is an excellent practical primer for researchers who wish to learn how to organize, present, and publish the results of their research. Written in a crystal-clear style with numerous examples, tables, and figures, the book shows how to produce a successful abstract, poster and/or manuscript for publication. This updated edition reflects the growing use of software in preparing and submitting presentations and publications. The posters and oral presentations chapters have been completely rewritten to cover PowerPoint technology. Emphasis is placed on learning how to create graphics for written research. This edition also includes new clinical examples.

Studyguide for Designing Clinical Research

Studyguide for Designing Clinical Research PDF Author: Cram101 Textbook Reviews
Publisher: Cram101
ISBN: 9781490239484
Category :
Languages : en
Pages : 170

Get Book

Book Description
Never HIGHLIGHT a Book Again Virtually all testable terms, concepts, persons, places, and events are included. Cram101 Textbook Outlines gives all of the outlines, highlights, notes for your textbook with optional online practice tests. Only Cram101 Outlines are Textbook Specific. Cram101 is NOT the Textbook. Accompanys: 9780521673761

Designing Clinical Research

Designing Clinical Research PDF Author: Stephen B. Hulley
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781782104
Category : Medical
Languages : en
Pages : 388

View

Book Description
This third edition sets the standard for providing a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This edition incorporates current research methodology and offers an updated syllabus for conducting a clinical research workshop.

Designing Clinical Research

Designing Clinical Research PDF Author: Stephen B. Hulley
Publisher: Lippincott Williams & Wilkins
ISBN: 9781608318049
Category : Medical
Languages : en
Pages : 367

View

Book Description
"This book provides a practical guide to planning, tabulating, formulating, and implementing clinical research, in an easy-to-use, readable presentation"--Provided by publisher.

Designing Clinical Research

Designing Clinical Research PDF Author: Warren S. Browner
Publisher: LWW
ISBN: 9781975174408
Category :
Languages : en
Pages : 472

View

Book Description
"For over 30 years, this title sets the standard as a practical guide for physicians, nurses, pharmacists and other practitioners involved in all forms of clinical and public health research. It presents the epidemiologic concepts in a reader-friendly way and suggests common sense approaches to the challenging judgments involved in designing, funding and implementing a study. Translated in many languages over the years, it is a manual for clinical research in it various flavors: clinical trials, observational epidemiology, translated science, patient-oriented research. Epidemiologic- terms and principles, presented advanced conceptual material in a practical and reader friendly way and suggested common sense approaches to many judgments involved in designing a study"--

Planning and Designing Clinical Research

Planning and Designing Clinical Research PDF Author: S.B. Martins
Publisher: Springer
ISBN: 9788847001398
Category : Medical
Languages : en
Pages : 48

View

Book Description
This manuscript is an introduction to the design and planning of clinical research. Practical issues are covered with a theoretical background. The refinement of a research question, searching and critically appraising the literature and management of references are discussed. Ethical concerns are raised throughout the development of the study protocol. Study designs are described and special emphasis is given to writing a protocol of a clinical trial. Sample selection and recruitment, variable measurement, randomization, follow up, statistical analysis, sample size and bias are covered. Tips on how to successfully write and publish the research report are provided.

Handbook for Clinical Research

Handbook for Clinical Research PDF Author: Flora Hammond, MD
Publisher: Demos Medical Publishing
ISBN: 1936287544
Category : Medical
Languages : en
Pages : 348

View

Book Description
The majority of physicians are poorly knowledgeable about statistics and research design, yet are expected to do clinical research and write articles (if in academia) or, at the very least, to read the literature critically and provide evidence-based care to patients. The basic skills involved are touched on very minimally in residency, but not in enough depth for an untrained investigator to successfully design or conduct a study, or analyze research findings in any meaningful way. This volume is intended as a “quick fix”, allowing readers to look up information rapidly about various design types and statistical methods to see what the pros, cons, and indications for each are. Research implementation, including regulatory issues and grant writing, is also covered. The book is unique in physical medicine and rehabilitation, and with the increased emphasis on outcomes measurement and push toward a national agenda for disability research, will appeal both to investigators planning and executing studies and clinicians looking to better understand how the findings impact their practice. A list of topics with an outline of headings for each of the sections is attached.

Clinical Trial Design

Clinical Trial Design PDF Author: Guosheng Yin
Publisher: John Wiley & Sons
ISBN: 0470581719
Category : Medical
Languages : en
Pages : 368

View

Book Description
A balanced treatment of the theories, methodologies, and design issues involved in clinical trials using statistical methods There has been enormous interest and development in Bayesian adaptive designs, especially for early phases of clinical trials. However, for phase III trials, frequentist methods still play a dominant role through controlling type I and type II errors in the hypothesis testing framework. From practical perspectives, Clinical Trial Design: Bayesian and Frequentist Adaptive Methods provides comprehensive coverage of both Bayesian and frequentist approaches to all phases of clinical trial design. Before underpinning various adaptive methods, the book establishes an overview of the fundamentals of clinical trials as well as a comparison of Bayesian and frequentist statistics. Recognizing that clinical trial design is one of the most important and useful skills in the pharmaceutical industry, this book provides detailed discussions on a variety of statistical designs, their properties, and operating characteristics for phase I, II, and III clinical trials as well as an introduction to phase IV trials. Many practical issues and challenges arising in clinical trials are addressed. Additional topics of coverage include: Risk and benefit analysis for toxicity and efficacy trade-offs Bayesian predictive probability trial monitoring Bayesian adaptive randomization Late onset toxicity and response Dose finding in drug combination trials Targeted therapy designs The author utilizes cutting-edge clinical trial designs and statistical methods that have been employed at the world's leading medical centers as well as in the pharmaceutical industry. The software used throughout the book is freely available on the book's related website, equipping readers with the necessary tools for designing clinical trials. Clinical Trial Design is an excellent book for courses on the topic at the graduate level. The book also serves as a valuable reference for statisticians and biostatisticians in the pharmaceutical industry as well as for researchers and practitioners who design, conduct, and monitor clinical trials in their everyday work.

Clinical Trials Design in Operative and Non Operative Invasive Procedures

Clinical Trials Design in Operative and Non Operative Invasive Procedures PDF Author: Kamal M.F. Itani
Publisher: Springer
ISBN: 3319538772
Category : Medical
Languages : en
Pages : 495

View

Book Description
The aim of this text is to provide the framework for building a clinical trial as it pertains to operative and non operative invasive procedures, how to get it funded and how to conduct such a trial up to publication of results The text provides all details of building a scientifically and ethically valid proposal, including how to build the infrastructure for a clinical trial and how to move it forward through various funding agencies. The text also presents various types of clinical trials, the use of implantable devices and FDA requirements, and adjuncts to clinical trials and interaction with industry Clinical Trials Design in Invasive Operative and Non Operative Procedures will be of interest to all specialists of surgery, anesthesiologists, interventional radiologists, gastroenterologists, cardiologists, and pulmonologists

Clinical Research

Clinical Research PDF Author: Manfred Stommel
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781735186
Category : Medical
Languages : en
Pages : 484

View

Book Description
This unique textbook integrates statistical concepts into evidence-based clinical practice and patient management. Research concepts and techniques are drawn from epidemiology, bio-statistics, and psychometrics, as well as educational and social science research. Clinical examples throughout the text illustrate practical and scientifically sound applications of the concepts. Data tables and research vignettes highlight statistical distributions involving probability. Methods to locate and utilize web-based information relevant to clinical research are discussed, and web URLs are provided. Further learning is encouraged by the inclusion of suggested activities, recommended readings, references, and a comprehensive glossary of research terms. Additional resources are available at a Connection Website, connection.LWW.com/go/stommel.

Publishing and Presenting Clinical Research

Publishing and Presenting Clinical Research PDF Author: Warren S. Browner
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781795067
Category : Medical
Languages : en
Pages : 230

View

Book Description
This book is an excellent practical primer for researchers who wish to learn how to organize, present, and publish the results of their research. Written in a crystal-clear style with numerous examples, tables, and figures, the book shows how to produce a successful abstract, poster and/or manuscript for publication. This updated edition reflects the growing use of software in preparing and submitting presentations and publications. The posters and oral presentations chapters have been completely rewritten to cover PowerPoint technology. Emphasis is placed on learning how to create graphics for written research. This edition also includes new clinical examples.

Studyguide for Designing Clinical Research

Studyguide for Designing Clinical Research PDF Author: Cram101 Textbook Reviews
Publisher: Cram101
ISBN: 9781490239484
Category :
Languages : en
Pages : 170

View

Book Description
Never HIGHLIGHT a Book Again Virtually all testable terms, concepts, persons, places, and events are included. Cram101 Textbook Outlines gives all of the outlines, highlights, notes for your textbook with optional online practice tests. Only Cram101 Outlines are Textbook Specific. Cram101 is NOT the Textbook. Accompanys: 9780521673761