Regulation of gene expression

Regulation of gene expression PDF Author: U Satyanarayana
Publisher: Elsevier Health Sciences
ISBN: 8131241831
Category : Medical
Languages : en
Pages : 21

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Regulation of gene expression Regulation of gene expression

Coordinated Regulation of Gene Expression

Coordinated Regulation of Gene Expression PDF Author: R. Clayton
Publisher: Springer Science & Business Media
ISBN: 1461322456
Category : Medical
Languages : en
Pages : 391

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Book Description
The Second Edinburgh International Workshop was held in September, 1984 and took as its topic the coordinated regulation of gene expression. The intention of this series of workshops is to promote exchange of ideas and data between scientists and clinicians whose interests span molecular and cell biology, development and differentiation, oncology, and genetic and developmental pathologies. It is hoped that such interdisciplinary discussions may give rise to fruitful insights. The meetings are structured to give ample time for discussion after each formal presentation and culminate in a session of general discussion which is reported at the end of the volume of proceedings. We are very grateful to the participants, all of whom participated in the discussion and whose contributions were essential to the success of the meeting. Novel ideas were often put forward and explored thoroughly from different angles. We normally expect to achieve quite rapid publication of the proceedings of the meeting and are grateful to authors who produced typescripts of their contributions expeditiously, but, as may sometimes be the case with multi-author works, some contributors had difficulty in meeting schedules for submitting manuscripts or corrections of the text of the discussion, and in one case we have been unable to publish any record of the contribution. Our committment to the publication of the discussion, allowing participants to make corrections to the transcript of the session, such as insertion of references and clarification of oral contributions, has also imposed some delay.

Regulation of Gene Expression in Enteropathogenic Bacteria, Volume II

Regulation of Gene Expression in Enteropathogenic Bacteria, Volume II PDF Author: Dongsheng Zhou
Publisher: Frontiers Media SA
ISBN: 2889664201
Category : Science
Languages : en
Pages : 516

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Book Description
Following the success of this Research Topic http://journal.frontiersin.org/ researchtopic/3298/regulation-of-gene-expression-in-enteropathogenic-bacteria, we are happy to launch a second edition of the project. Pathogenic bacteria have evolved numerous strategies to survive in and to attack hosts, which can be reflected by transcriptional and posttranscriptional changes in specific genes especially including those encoding virulence determinants. Regulation of gene expression by regulatory proteins and non-coding RNAs enables the pathogens to adapt their metabolic needs and to coordinately express virulence determinants during different stages of infection.

Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria

Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria PDF Author: Frans J. de Bruijn
Publisher: John Wiley & Sons
ISBN: 1119004896
Category : Science
Languages : en
Pages : 1472

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Book Description
Bacteria in various habitats are subject to continuously changing environmental conditions, such as nutrient deprivation, heat and cold stress, UV radiation, oxidative stress, dessication, acid stress, nitrosative stress, cell envelope stress, heavy metal exposure, osmotic stress, and others. In order to survive, they have to respond to these conditions by adapting their physiology through sometimes drastic changes in gene expression. In addition they may adapt by changing their morphology, forming biofilms, fruiting bodies or spores, filaments, Viable But Not Culturable (VBNC) cells or moving away from stress compounds via chemotaxis. Changes in gene expression constitute the main component of the bacterial response to stress and environmental changes, and involve a myriad of different mechanisms, including (alternative) sigma factors, bi- or tri-component regulatory systems, small non-coding RNA’s, chaperones, CHRIS-Cas systems, DNA repair, toxin-antitoxin systems, the stringent response, efflux pumps, alarmones, and modulation of the cell envelope or membranes, to name a few. Many regulatory elements are conserved in different bacteria; however there are endless variations on the theme and novel elements of gene regulation in bacteria inhabiting particular environments are constantly being discovered. Especially in (pathogenic) bacteria colonizing the human body a plethora of bacterial responses to innate stresses such as pH, reactive nitrogen and oxygen species and antibiotic stress are being described. An attempt is made to not only cover model systems but give a broad overview of the stress-responsive regulatory systems in a variety of bacteria, including medically important bacteria, where elucidation of certain aspects of these systems could lead to treatment strategies of the pathogens. Many of the regulatory systems being uncovered are specific, but there is also considerable “cross-talk” between different circuits. Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria is a comprehensive two-volume work bringing together both review and original research articles on key topics in stress and environmental control of gene expression in bacteria. Volume One contains key overview chapters, as well as content on one/two/three component regulatory systems and stress responses, sigma factors and stress responses, small non-coding RNAs and stress responses, toxin-antitoxin systems and stress responses, stringent response to stress, responses to UV irradiation, SOS and double stranded systems repair systems and stress, adaptation to both oxidative and osmotic stress, and desiccation tolerance and drought stress. Volume Two covers heat shock responses, chaperonins and stress, cold shock responses, adaptation to acid stress, nitrosative stress, and envelope stress, as well as iron homeostasis, metal resistance, quorum sensing, chemotaxis and biofilm formation, and viable but not culturable (VBNC) cells. Covering the full breadth of current stress and environmental control of gene expression studies and expanding it towards future advances in the field, these two volumes are a one-stop reference for (non) medical molecular geneticists interested in gene regulation under stress.

Index Medicus

Index Medicus PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 2074

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Medical Subject Headings

Medical Subject Headings PDF Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Subject headings
Languages : en
Pages :

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Genetics

Genetics PDF Author: Leland Hartwell
Publisher: McGraw-Hill Companies
ISBN:
Category : Genetics
Languages : en
Pages : 904

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Book Description
"Genetics: From Genes to Genomes" is a cutting-edge, introductory genetics text authored by an unparalleled author team, including Nobel Prize winner, Leland Hartwell. The Third Edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between early genetics understanding and the new molecular discoveries that have changed the way the field of genetics is viewed.

Fundamentals of Genetics

Fundamentals of Genetics PDF Author: Gurbachan S. Miglani
Publisher: Alpha Science International Limited
ISBN:
Category : Science
Languages : en
Pages : 668

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Book Description
Deals with topics in Mendelian genetics, cytology, biochemical genetics, mutagenesis, extranuclear and extrachromosomal inheritance, molecular genetics, developmental genetics, human genetics, population genetics, evolutionary genetics and biostatistics.

Regulation of Gene Expression in Escherichia Coli

Regulation of Gene Expression in Escherichia Coli PDF Author: E. C. C. Lin
Publisher: Springer
ISBN:
Category : Juvenile Nonfiction
Languages : en
Pages : 616

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Book Description
This up-to-date guide focuses on the understanding of key regulatory mechanisms governing gene expression in Escherichia coli. Studies of E. coli not only provide the first models of gene regulation, but research continues to yield different control mechanisms.

Regulation of Gene Expression

Regulation of Gene Expression PDF Author: Gary H. Perdew
Publisher: Humana Press
ISBN: 9781627038089
Category : Science
Languages : en
Pages : 333

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Book Description
The use of molecular biology and biochemistry to study the regulation of gene expression has become a major feature of research in the biological sciences. Many excellent books and reviews exist that examine the experimental methodology employed in specific areas of molecular biology and regulation of gene expression. However, we have noticed a lack of books, especially textbooks, that provide an overview of the rationale and general experimental approaches used to examine chemically or disease-mediated alterations in gene expression in mammalian systems. For example, it has been difficult to find appropriate texts that examine specific experimental goals, such as proving that an increased level of mRNA for a given gene is attributable to an increase in transcription rates. Regulation of Gene Expression: Molecular Mechanisms is intended to serve as either a textbook for graduate students or as a basic reference for laboratory personnel. Indeed, we are using this book to teach a graduate-level class at The Pennsylvania State University. For more details about this class, please visit http://moltox. cas. psu. edu and select “Courses. ” The goal for our work is to provide an overview of the various methods and approaches to characterize possible mechanisms of gene regulation. Further, we have attempted to provide a framework for students to develop an understanding of how to determine the various mechanisms that lead to altered activity of a specific protein within a cell.

Regulation of Gene Expression and Brain Function

Regulation of Gene Expression and Brain Function PDF Author: Paul J. Harrison
Publisher: Springer Verlag
ISBN:
Category : Medical
Languages : en
Pages : 84

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Book Description


Regulation of gene expression

Regulation of gene expression PDF Author: U Satyanarayana
Publisher: Elsevier Health Sciences
ISBN: 8131241831
Category : Medical
Languages : en
Pages : 21

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Book Description
Regulation of gene expression Regulation of gene expression

Nutrition and Gene Expression

Nutrition and Gene Expression PDF Author: Carolyn D. Berdanier
Publisher: CRC Press
ISBN: 9780849369612
Category : Medical
Languages : en
Pages : 600

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Book Description
Nutrition and Gene Expression is devoted to exploring the tissue-specific and developmental aspects of the interaction between nutrients and the genome. The book discusses chemical sensitivity in relation to the ability of cells to detect nutrients; reviews the means by which lower organisms respond to nutrients; and provides examples on how each of the classes of nutrients affects genetic transcription, mRNA translation or stability. The receptor-mediated actions of vitamin D and retinoic acid on gene expression are discussed, including the case of bone formation and dissolution. Other important topics covered in the volume include newly discovered effects of fatty acids on regulating gene expression, the effects of diet on mRNA editing, the interplay between dietary carbohydrates and proteins in regulating metabolism of liver cells, the effects of metal ions on protein synthesis, and much more. Nutrition and Gene Expression is an important reference for nutritionists, physiologists, biochemists, clinical nutritionists, pharmaceutical researchers, geneticists, and food scientists.

Non-coding RNAs and Epigenetic Regulation of Gene Expression

Non-coding RNAs and Epigenetic Regulation of Gene Expression PDF Author: Kevin V. Morris
Publisher: Horizon Scientific Press
ISBN: 9781904455943
Category : Science
Languages : en
Pages : 216

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Book Description
Non-coding RNAs potentially play an active role in modulating gene transcription and epigenetic states. Several genes in differentiated cells may be under some form of RNA-based transcriptional and epigenetic regulatory control. This form of regulation may be controlled by selective pressures and influence the adaptability of the cell. The concept that RNA can control epigenetic states impacts our understanding of the basic fabric of the cell and may have therapeutic potential. Many studies have been carried out on the modulation of gene transcription by non-coding RNAs. This book, written by a group of distinguished scientists, represents an important overview and summary of the field to date. The 13 chapters are organized into three sections: a) Non-coding RNAs: Form, Function and Diversity; b) Non-coding RNAs: Gene Regulation and Epigenetics; and c) Non-coding RNAs: Disease and Therapeutics. This up-to-date volume is an essential book for those working in the area and represents a major information resource on current research in the fast-moving fields of epigenetics, the regulation of gene expression, and RNA research.

Gene Expression and Regulation in Mammalian Cells

Gene Expression and Regulation in Mammalian Cells PDF Author: Fumiaki Uchiumi
Publisher: BoD – Books on Demand
ISBN: 9535138553
Category : Medical
Languages : en
Pages : 336

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Book Description
"Central dogma" was presented by Dr. Francis Crick 60 years ago. The information of nucleotide sequences on DNAs is transcribed into RNAs by RNA polymerases. We learned the mechanisms of how transcription determines function of proteins and behaviour of cells and even how it brings appearances of organisms. This book is intended for scientists and medical researchers especially who are interested in the relationships between transcription and human diseases. This volume consists of an introductory chapter and 14 chapters, divided into 4 parts. Each chapter is written by experts in the basic scientific field. A collection of articles presented by active and laboratory-based investigators provides recent advances and progresses in the field of transcriptional regulation in mammalian cells.

RNA and the Regulation of Gene Expression

RNA and the Regulation of Gene Expression PDF Author: Kevin V. Morris
Publisher: Horizon Scientific Press
ISBN: 9781904455257
Category : Science
Languages : en
Pages : 228

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Book Description
The role of RNA in regulating gene expression has become a topic of intense interest. In this book, internationally recognized experts in RNA research explore and discuss the methods whereby RNA can regulate gene expression with examples in yeast, Drosophila, mammals, and viral infection, as well as highlight the application of this knowledge in therapeutics and research. Topics include: gene silencing and gene activation, the hammerhead ribozyme, epigenetic regulation, RNAi, microRNA, and pyknons. This comprehensive publication is intended for readers with teaching or research interests in RNA, the regulation of gene expression, genetics, genomics, and molecular biology.

Regulation of Gene Expression in Animal Viruses

Regulation of Gene Expression in Animal Viruses PDF Author: Luis Carrasco
Publisher: Springer
ISBN: 9781461362715
Category : Medical
Languages : en
Pages : 325

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Book Description
Viruses, being obligatory parasites of their host cells, rely on a vast supply of cellular components for their replication, regardless of whether infection leads to cell death or to the state of persistence. Animal viruses are providing scientists with relatively simple models to study the molecular biology of genome replication and gene expression. Whereas viruses use, in general, pathways of macromolecular biosynthesis common to the host cell, they have a cunning ability to adopt unusual mechanisms of gene expression and gene replication, provided these special pathways offer an advantage in competition for cellular resources. Any study of viral gene expression and replication is likely to lead also to new insights in cellular metabolism. The discoveries of cis-acting regulatory elements in transcription, the phenomenon of splicing of pre mRNA, and cap-dependent and cap-independent initiation of translation may be cited as examples. In addition, animal virus genomes contain elements and encode proteins that are very useful for the design of vectors for gene cloning and expression in mammalian cells. Apart from the basic interest in their biology, viruses have gained notoriety, of course, because they are pathogens. Human animal viruses may cause diseases ranging from the deadly (AIDS) to the benign (common cold). All studies on animal viruses potentially lead to the development of tools for their control, be it through prevention by immunization or treatment with antiviral drugs. Finally, viruses have yielded invaluable reagents in molecular biology as, for example, the vaccinia virus vector for the expression of foreign genes.

Coordinated Regulation of Gene Expression

Coordinated Regulation of Gene Expression PDF Author: R. Clayton
Publisher: Springer Science & Business Media
ISBN: 1461322456
Category : Medical
Languages : en
Pages : 391

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Book Description
The Second Edinburgh International Workshop was held in September, 1984 and took as its topic the coordinated regulation of gene expression. The intention of this series of workshops is to promote exchange of ideas and data between scientists and clinicians whose interests span molecular and cell biology, development and differentiation, oncology, and genetic and developmental pathologies. It is hoped that such interdisciplinary discussions may give rise to fruitful insights. The meetings are structured to give ample time for discussion after each formal presentation and culminate in a session of general discussion which is reported at the end of the volume of proceedings. We are very grateful to the participants, all of whom participated in the discussion and whose contributions were essential to the success of the meeting. Novel ideas were often put forward and explored thoroughly from different angles. We normally expect to achieve quite rapid publication of the proceedings of the meeting and are grateful to authors who produced typescripts of their contributions expeditiously, but, as may sometimes be the case with multi-author works, some contributors had difficulty in meeting schedules for submitting manuscripts or corrections of the text of the discussion, and in one case we have been unable to publish any record of the contribution. Our committment to the publication of the discussion, allowing participants to make corrections to the transcript of the session, such as insertion of references and clarification of oral contributions, has also imposed some delay.